⸻ AI-native clinical development

Making the patient computable

AICURA turns fragmented, multimodal clinical data into one computable AI-ready substrate, so trials in neurodegeneration are designed, enriched, and run with far greater precision.

The problem ⸻

Models are not the bottleneck in AI-driven drug development, the data substrate is

The signal that separates responders from non-responders, and fast progressors from slow, sits across imaging, fluid biomarkers, and longitudinal trajectories that trial systems never bring together. AICURA makes that data computable once, so every analysis and every model runs on the same integrated view of the patient.

The pLATFORM ⸻
SUBSTRATE

Patient graph

Brings each patient's fragmented history, across imaging, biomarkers, and time, into a single computable view that models can actually use.

product

Data Layer

The environment clinical teams work in directly. They query, explore, and model against one harmonized substrate, without re-engineering the data for every analysis, and own both the data and the work built on it.

MODELS

AI Layer

The models that turn the substrate into trial enrichment. State-of-the-art multimodal architectures today, extending to large pre-trained models across complex data modalities.

The FOCUS ⸻

Built where the biology is most complex neurodegeneration

One of the tehrapeutic areas where patients differ most in how they progress and whether they respond, a computable substrate turns messy trial histories into sharper, smaller, faster studies.

A

Trial design & simulation

Test eligibility, power, and design choices against real historical data before committing a protocol.

B

Prognostic & predictive enrichment

Select the patients a trial needs, cutting sample size and screen-failure rates without losing power.

C

Eligibility & feasibility

Test inclusion and exclusion criteria against real data to cut screen failures before a protocol locks.

D

Digital biomarkers

Derive progression markers from multimodal data to sharpen inclusion and exclusion endpoints

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